Tranexamic Acid: The New Ally for Treating Melasma and Skin Pigmentation By Dr. Carlos González, Dermatologist in Bogotá

What is Tranexamic Acid?

Tranexamic acid (TXA) is a synthetic derivative of lysine, traditionally used as an antifibrinolytic to control bleeding. However, in recent years, it has gained significant traction in dermatology for its effectiveness in treating hyperpigmentation such as melasma, post-inflammatory dark spots, and chronic sun pigmentation.

Its mechanism of action includes the inhibition of melanocyte activation induced by inflammatory mediators.

Why is it trending in 2025?

Recent clinical studies have shown that topical, oral, or microinjected tranexamic acid can significantly improve melasma and other pigmentation disorders without the side effects of more aggressive treatments like hydroquinone or certain lasers.

How is it applied?

Tranexamic acid can be used in different forms:

• Topical (creams, serums): ideal for at-home use.

• Oral : under dermatological supervision.

• Intradermal or mesotherapy: in controlled in-office sessions.

At my clinic in Bogotá, I conduct a thorough evaluation of each skin type and pigmentation issue to select the appropriate combination of therapies.

Key Benefits of Tranexamic Acid

• ❌ Less irritating than other depigmenting agents.

• ✅ Suitable for sensitive skin.

• ✨ Improves overall skin tone.

• ⚡ Can be combined with vitamin C, niacinamide, and retinoids.

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Comprehensive In-Office Treatment

At Dr. Carlos González’s dermatology clinic in Bogotá, we offer:

• Personalized protocols with tranexamic acid.

• Combined chemical peels.

• Non-ablative fractional laser therapy.

• Guided professional skincare routines.

• Monthly medical follow-ups.

  
  

Frequently Asked Questions (FAQ)

How soon will I see results? On average, between 8 to 12 weeks with consistent use.

Are there side effects? Topically, it is very safe. Oral use requires supervision due to a potential thrombotic risk in predisposed individuals.

Is it suitable for all skin types? Yes, including darker phototypes, with proper medical monitoring.

Conclusion

Tranexamic acid is one of the most promising and safest options for managing melasma and skin pigmentation. If you're looking for an effective dermatological treatment in Bogotá, book a consultation with Dr. Carlos González to start a personalized plan grounded in science and clinical experience.